DTI is useful for early diagnosis of MSA, separating from Parkinson′s disease: Evidence for subclinical detection of cerebellar pathology
نویسندگان
چکیده
Fig 2. A. ADC values of the middle cerebellar peduncle showed significant group differences (p<0.0001): MSA-c > MSA-p > PD = Normal. B. ADC values of the posterior putamen showed significant group differences (p<0.0001): MSA-p > MSA-c = PD = Normal. The MSA-mixed group (n=4) is not shown for the clarity. Error bar= 1 SD. C. SARA scores that assess the severity of cerebellar ataxia correlate significantly positively with ADC values of the middle cerebellar peduncle. *Patient A showed DOPA-responsive parkinsonism and was initially diagnosed as PD. She showed increased ADC in the middle cerebellar peduncle. [F]FDG-PET showed reduced FDG uptake in the putamen and the cerebellum, which is consistent with MSA. *n=16 (Three cases were missing due to the absence of SARA scores).
منابع مشابه
Diffusion tensor imaging in the characterization of multiple system atrophy
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